Gene: ZNF383

Alternate names for this Gene: HSD17|Zfp383

Gene Summary: The protein encoded by this gene is a KRAB-related zinc finger protein that inhibits the transcription of some MAPK signaling pathway genes. The repressor activity resides in the KRAB domain of the encoded protein.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.12

Description of this Gene: zinc finger protein 383

Type of Gene: protein-coding

rs1234256 in ZNF383 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs1234261 in ZNF383 gene and Otosclerosis PMID 19230858 2009 A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis.