Gene: ZRANB3

Alternate names for this Gene: 4933425L19Rik|AH2

Gene Summary:

Gene is located in Chromosome: 2

Location in Chromosome : 2q21.3

Description of this Gene: zinc finger RANBP2-type containing 3

Type of Gene: protein-coding

Gene: RAB3GAP1

Alternate names for this Gene: P130|RAB3GAP|RAB3GAP130|WARBM1

Gene Summary: This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.

Gene is located in Chromosome: 2

Location in Chromosome : 2q21.3

Description of this Gene: RAB3 GTPase activating protein catalytic subunit 1

Type of Gene: protein-coding

rs3739028 in ZRANB3;RAB3GAP1 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.