Variant: rs1019340046 

    present in Gene: TP53
    present in Chromosome: 17
    Position on Chromosome: 7674225
    Alleles of this Variant: C/T

rs1019340046 in TP53 gene and Neoplastic Syndromes, Hereditary PMID 8633021 1996 Dominant-negative p53 mutations selected in yeast hit cancer hot spots.

PMID 16861262 2007 Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers.

PMID 12826609 2003 Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis.

PMID 19652052 2009 2009 version of the Chompret criteria for Li Fraumeni syndrome.