Variant: rs1049380

present in Gene: ITPR2 present in Chromosome: 12 Position on Chromosome: 26336611 Alleles of this Variant: G/T

rs1049380 in ITPR2 gene and Renal Cell Carcinoma PMID 22010048 2012 We identified two common variants in linkage disequilibrium, rs718314 and rs1049380 (r(2) = 0.64, D ' = 0.84), in the inositol 1,4,5-triphosphate receptor, type 2 (ITPR2) gene on 12p11.23 as novel susceptibility loci for RCC (P = 8.89 × 10(-10) and P = 6.07 × 10(-9), respectively, in meta-analysis) with an allelic odds ratio of 1.19 [95% confidence interval (CI): 1.13-1.26] for rs718314 and 1.18 (95% CI: 1.12-1.25) for rs1049380.

PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.