present in Gene: ATG16L2
present in Chromosome: 11
Position on Chromosome: 72822491
Alleles of this Variant: C/T
rs11235604 in
ATG16L2 gene and
Crohn Disease
PMID 23850713 2014 Further analysis of the 11q13 locus revealed a non-synonymous single nucleotide polymorphism (SNP) (R220W/rs11235604) in the evolutionarily conserved region of ATG16L2 with stronger association (OR=1.61, combined p=2.44×10(-12)) than rs11235667, suggesting ATG16L2 as a novel susceptibility gene for CD and rs11235604 to be a potential causal variant of the association.