Variant: rs113994087 

    present in Gene: ALK
    present in Chromosome: 2
    Position on Chromosome: 29209798
    Alleles of this Variant: C/A;T

rs113994087 in ALK gene and Brain Neoplasms PMID 22072639 2011 Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.

rs113994087 in ALK gene and Mammary Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs113994087 in ALK gene and NEUROBLASTOMA, SUSCEPTIBILITY TO PMID 21242967 2011 The constitutive activity of the ALK mutated at positions F1174 or R1275 impairs receptor trafficking.

PMID 18923525 2008 Activating mutations in ALK provide a therapeutic target in neuroblastoma.

PMID 22072639 2011 Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.

PMID 21838707 2011 Activating ALK mutations found in neuroblastoma are inhibited by Crizotinib and NVP-TAE684.

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

PMID 18923523 2008 Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma.