present in Gene: TOMM40
present in Chromosome: 19
Position on Chromosome: 44899959
Alleles of this Variant: C/G;T
rs115881343 in
TOMM40 gene and
Mental deterioration
PMID 24468470 2014 We found 2 independent associations among European-Americans in the 19q13.32 region: rs769449 (APOE intron; p = 3.1 × 10(-20)) and rs115881343 (TOMM40 intron; p = 6.6 × 10(-11)). rs769449 was also associated with cognitive decline among African-Americans (p = 0.005), but rs115881343 was not.