present in Gene: CASZ1
present in Chromosome: 1
Position on Chromosome: 10739520
Alleles of this Variant: T/C
rs12046278 in
CASZ1 gene and
Diastolic blood pressure
PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.
rs12046278 in
CASZ1 gene and
Hypertensive disease
PMID 31545351 2019 The known hypertension locus, CASZ1, was a top finding among EAs (P = 1.1 × 10-8) and in the race-combined analysis (P = 1.5 × 10-9) using the normotensive control group (rs12046278, odds ratio = 0.71 (95% confidence interval: 0.6-0.8)).
rs12046278 in
CASZ1 gene and
Systolic Pressure
PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.