Variant: rs121909244 

    present in Gene: PPARG
    present in Chromosome: 3
    Position on Chromosome: 12434111
    Alleles of this Variant: C/A;T

rs121909244 in PPARG gene and Familial Partial Lipodystrophy, Type 3 PMID 10622252 2000 Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension.

PMID 25157153 2014 Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes.

PMID 15254591 2004 Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma.

PMID 22461176 2012 Peroxisome proliferator-activated receptor-γ protects against vascular aging.