Variant: rs121909621 

    present in Gene: FGB
    present in Chromosome: 4
    Position on Chromosome: 154569703
    Alleles of this Variant: T/G

rs121909621 in FGB gene and Congenital hypofibrinogenemia PMID 10666208 2000 Missense mutations in the human beta fibrinogen gene cause congenital afibrinogenemia by impairing fibrinogen secretion.

PMID 25427968 2015 Clinical and molecular characterisation of 21 patients affected by quantitative fibrinogen deficiency.

PMID 11468164 2001 The impaired polymerization of fibrinogen Longmont (Bbeta166Arg-->Cys) is not improved by removal of disulfide-linked dimers from a mixture of dimers and cysteine-linked monomers.

PMID 15070683 2004 Missense or splicing mutation? The case of a fibrinogen Bbeta-chain mutation causing severe hypofibrinogenemia.