Variant: rs121964951

present in Gene: KLKB1 present in Chromosome: 4 Position on Chromosome: 186257283 Alleles of this Variant: G/A

rs121964951 in KLKB1 gene and Prekallikrein deficiency PMID 17598838 2007 A new type of plasma prekallikrein deficiency associated with homozygosity for Gly104Arg and Asn124Ser in apple domain 2 of the heavy-chain region.

PMID 14652634 2003 Severe prekallikrein (Fletcher factor) deficiency due to a compound heterozygosis (383Trp stop codon and Cys529Tyr).