present in Gene: HERC2
present in Chromosome: 15
Position on Chromosome: 28120472
Alleles of this Variant: A/G
rs12913832 in
HERC2 gene and
Asthma
PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.
rs12913832 in
HERC2 gene and
Eye Color
PMID 23486544 2013 Genetics of eye colours in different rural populations on the Silk Road.
PMID 23548203 2013 Additionally, we identified a significant interaction between the SNPs rs7173419 and rs12913832 in the OCA2 gene region on brown eye color (P-value for interaction = 3.8 × 10(-3)).
PMID 20463881 2010 Digital quantification of human eye color highlights genetic association of three new loci.
PMID 20585627 2010 Web-based, participant-driven studies yield novel genetic associations for common traits.
rs12913832 in
HERC2 gene and
Glaucoma
PMID 30104761 2018 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
rs12913832 in
HERC2 gene and
Hair Color
PMID 30531825 2018 Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.
PMID 18483556 2008 A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.
PMID 20585627 2010 Web-based, participant-driven studies yield novel genetic associations for common traits.
PMID 23548203 2013 Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
rs12913832 in
HERC2 gene and
Regular astigmatism - corneal
PMID 30306274 2018 Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci.
rs12913832 in
HERC2 gene and
Skin Pigmentation
PMID 25963972 2015 Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up.
PMID 30166351 2018 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.
rs12913832 in
HERC2 gene and
Suntan
PMID 23548203 2013 Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
PMID 30166351 2018 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.
PMID 29739929 2018 Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.
rs12913832 in
HERC2 gene and
melanoma
PMID 21926416 2011 Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.