present in Gene: LRP2
present in Chromosome: 2
Position on Chromosome: 169261301
Alleles of this Variant: C/T
rs12988804 in
LRP2 gene and
Disease recurrence
PMID 28739605 2017 Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis.
rs12988804 in
LRP2 gene and
Multiple Sclerosis
PMID 28739605 2017 In the pooled results, using these three unique longitudinal MS cohorts, we discovered one novel locus (<i>LRP2</i>; most significant single nucleotide polymorphism rs12988804) that reached genome-wide significance in predicting relapse risk (HR=2.18, p=3.30×10<sup>-8</sup>).