present in Gene: KCNN3
present in Chromosome: 1
Position on Chromosome: 154841877
Alleles of this Variant: C/T
rs13376333 in
KCNN3 gene and
Atrial Fibrillation
PMID 20173747 2010 We identified an association on chromosome 1q21 to lone AF (rs13376333, adjusted odds ratio = 1.56; P = 6.3 x 10(-12)), and we replicated this association in two independent cohorts with lone AF (overall combined odds ratio = 1.52, 95% CI 1.40-1.64; P = 1.83 x 10(-21)). rs13376333 is intronic to KCNN3, which encodes a potassium channel protein involved in atrial repolarization.