Variant: rs137852659

present in Gene: FGF8 present in Chromosome: 10 Position on Chromosome: 101775769 Alleles of this Variant: G/T

rs137852659 in FGF8 gene and HYPOGONADOTROPIC HYPOGONADISM 6 WITH OR WITHOUT ANOSMIA PMID 18596921 2008 Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice.

PMID 23643382 2013 Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.