Variant: rs141853578 

    present in Gene: CFI
    present in Chromosome: 4
    Position on Chromosome: 109764664
    Alleles of this Variant: C/T

rs141853578 in CFI gene and Age related macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs141853578 in CFI gene and Exudative age-related macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs141853578 in CFI gene and Geographic Atrophy PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs141853578 in CFI gene and HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 3 PMID 19846853 2009 Atypical hemolytic-uremic syndrome.

PMID 19821824 2010 Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom.

PMID 16621965 2006 Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.

PMID 17106690 2007 A missense mutation in factor I (IF) predisposes to atypical haemolytic uraemic syndrome.

PMID 15173250 2004 Complement factor I: a susceptibility gene for atypical haemolytic uraemic syndrome.

PMID 20513133 2010 Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome.

rs141853578 in CFI gene and MACULAR DEGENERATION, AGE-RELATED, 13 PMID 23685748 2013 A functional variant in the CFI gene confers a high risk of age-related macular degeneration.

rs141853578 in CFI gene and exudative macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.