Variant: rs143853590

present in Gene: MAP3K1 present in Chromosome: 5 Position on Chromosome: 56875191 Alleles of this Variant: G/A;C;T

rs143853590 in MAP3K1 gene and 46,XY SEX REVERSAL 6 PMID 21129722 2010 Mutations in MAP3K1 cause 46,XY disorders of sex development and implicate a common signal transduction pathway in human testis determination.

PMID 18947601 2006 Consensus statement on management of intersex disorders.