present in Gene: LOC102725112;NEBL
present in Chromosome: 10
Position on Chromosome: 20879174
Alleles of this Variant: C/G
rs16921209 in
LOC102725112;NEBL gene and
Coronary Aneurysm
PMID 27171184 2016 Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease.
rs16921209 in
LOC102725112;NEBL gene and
Mucocutaneous Lymph Node Syndrome
PMID 27171184 2016 Upon our previous genotyping data of 157 valid KD subjects, a genome-wide association study (GWAS) has been conducted among 11 (7%) CAA-developed KD patients to reveal five significant genetic variants passed pre-defined thresholds and resulted in two novel susceptibility protein-coding genes, which are NEBL (rs16921209 (P = 7.44 × 10(-9); OR = 32.22) and rs7922552 (P = 8.43 × 10(-9); OR = 32.0)) and TUBA3C (rs17076896 (P = 8.04 × 10(-9); OR = 21.03)).