present in Gene: HLA-DQB1;HLA-DQB1-AS1
present in Chromosome: 6
Position on Chromosome: 32660056
Alleles of this Variant: A/G
rs1770 in
HLA-DQB1;HLA-DQB1-AS1 gene and
Diabetes Mellitus, Insulin-Dependent
PMID 31152121 2019 We identified four T1D risk loci reaching genome-wide significance in the Chinese Han population, including two novel loci, rs4320356 near <i>BTN3A1</i> (odds ratio [OR] 1.26, <i>P</i> = 2.70 × 10<sup>-8</sup>) and rs3802604 in <i>GATA3</i> (OR 1.24, <i>P</i> = 2.06 × 10<sup>-8</sup>), and two previously reported loci, rs1770 in MHC (OR 4.28, <i>P</i> = 2.25 × 10<sup>-232</sup>) and rs705699 in <i>SUOX</i> (OR 1.46, <i>P</i> = 7.48 × 10<sup>-20</sup>).