Variant: rs17710891 

    present in Gene: SMO
    present in Chromosome: 7
    Position on Chromosome: 129209348
    Alleles of this Variant: G/A;C

rs17710891 in SMO gene and Carcinoma, Basal Cell PMID 25759020 2015 Smoothened variants explain the majority of drug resistance in basal cell carcinoma.

PMID 19726788 2009 Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

PMID 22679179 2012 Vismodegib.

rs17710891 in SMO gene and Medulloblastoma PMID 22679179 2012 Vismodegib.

PMID 19726788 2009 Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.