present in Gene: TCF3
present in Chromosome: 19
Position on Chromosome: 1650135
Alleles of this Variant: A/C;G
rs1860661 in
TCF3 gene and
Hodgkin Disease
PMID 24920014 2014 We identify a novel variant at 19p13.3 associated with HL (rs1860661; odds ratio (OR)=0.81, 95% confidence interval (95% CI) = 0.76-0.86, P(combined) = 3.5 × 10(-10)), located in intron 2 of TCF3 (also known as E2A), a regulator of B- and T-cell lineage commitment known to be involved in HL pathogenesis.