present in Gene: SYT14
present in Chromosome: 1
Position on Chromosome: 209942767
Alleles of this Variant: G/A
rs2205986 in
SYT14 gene and
Chemical and Drug Induced Liver Injury
PMID 30013178 2018 Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis.
rs2205986 in
SYT14 gene and
Multiple Sclerosis
PMID 30013178 2018 Analysis of an independent cohort of IFN-β-treated MS patients identified via electronic medical records showed that rs2205986 was also associated with increased peak levels of aspartate aminotransferase (P = 7.6 × 10<sup>-5</sup>) and alkaline phosphatase (P = 4.9 × 10<sup>-4</sup>).