present in Gene: PAX4
present in Chromosome: 7
Position on Chromosome: 127614497
Alleles of this Variant: G/A;T
rs2233578 in
PAX4 gene and
Diabetes Mellitus, Ketosis-Prone
PMID 15509590 2004 Clinical investigation of the homozygous Arg133Trp carriers and of the Arg37Trp carrier demonstrated a more severe alteration in insulin secretory reserve, during a glucagon-stimulation test, compared to other KPD subjects.