Variant: rs2241880 

    present in Gene: SCARNA5;ATG16L1
    present in Chromosome: 2
    Position on Chromosome: 233274722
    Alleles of this Variant: A/G

rs2241880 in SCARNA5;ATG16L1 gene and Crohn Disease PMID 17435756 2007 Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.

PMID 22412388 2012 A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.

PMID 18587394 2008 Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

PMID 17684544 2007 Systematic association mapping identifies NELL1 as a novel IBD disease gene.

rs2241880 in SCARNA5;ATG16L1 gene and Inflammatory Bowel Disease 10 PMID 27273576 2016 The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1.

PMID 18985712 2009 Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children.

PMID 18047540 2008 ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands.

PMID 25645662 2016 The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon.

PMID 24656308 2014 Autophagy genes variants and paediatric Crohn's disease phenotype: a single-centre experience.

PMID 17435756 2007 Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.

PMID 17484864 2007 A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.

PMID 17200669 2007 A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.

PMID 24553140 2014 A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.

PMID 18499543 2008 ATG16L1 and IL23 receptor (IL23R) genes are associated with disease susceptibility in Hungarian CD patients.

PMID 19659808 2009 Autophagy 16-like 1 rs2241880 G allele is associated with Crohn's disease in German children.