Variant: rs2273500

present in Gene: CHRNA4 present in Chromosome: 20 Position on Chromosome: 63355597 Alleles of this Variant: T/C

rs2273500 in CHRNA4 gene and Smoking PMID 26440539 2015 Importantly, rs2273500-C was associated with increased lung cancer risk (N=28 998, odds ratio=1.06 and 95% confidence interval=1.00-1.12), likely through its effect on smoking, as rs2273500-C was no longer associated with lung cancer after adjustment for smoking.