Variant: rs2284378

present in Gene: RALY present in Chromosome: 20 Position on Chromosome: 34000289 Alleles of this Variant: T/C;G

rs2284378 in RALY gene and Breast Carcinoma PMID 22976474 2012 SNP rs2284378 at 20q11 was associated with ER-negative breast cancer (combined two-stage OR = 1.16; P = 1.1 × 10(-8)) but showed a weaker association with overall breast cancer (OR = 1.08, P = 1.3 × 10(-6)) based on 17 869 cases and 43 745 controls and no association with ER-positive disease (OR = 1.01, P = 0.67) based on 9965 cases and 22 902 controls.

rs2284378 in RALY gene and Malignant neoplasm of breast PMID 22976474 2012 SNP rs2284378 at 20q11 was associated with ER-negative breast cancer (combined two-stage OR = 1.16; P = 1.1 × 10(-8)) but showed a weaker association with overall breast cancer (OR = 1.08, P = 1.3 × 10(-6)) based on 17 869 cases and 43 745 controls and no association with ER-positive disease (OR = 1.01, P = 0.67) based on 9965 cases and 22 902 controls.

rs2284378 in RALY gene and melanoma PMID 21983787 2011 Genome-wide association study identifies three new melanoma susceptibility loci.