present in Gene: PLCH2
present in Chromosome: 1
Position on Chromosome: 2461209
Alleles of this Variant: G/C
rs2477686 in
PLCH2 gene and
Azoospermia
PMID 22197933 2011 A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.
rs2477686 in
PLCH2 gene and
Non-obstructive azoospermia
PMID 22197933 2011 The combined analyses identified significant (P < 5.0 × 10(-8)) associations between NOA risk and common variants near PRMT6 (rs12097821 at 1p13.3: odds ratio (OR) = 1.25, P = 5.7 × 10(-10)), PEX10 (rs2477686 at 1p36.32: OR = 1.39, P = 5.7 × 10(-12)) and SOX5 (rs10842262 at 12p12.1: OR = 1.23, P = 2.3 × 10(-9)).