Variant: rs281865417 

    present in Gene: COX2;COX1
    present in Chromosome: MT
    Position on Chromosome: 6277
    Alleles of this Variant: G/A

rs281865417 in COX2;COX1 gene and Colorectal Carcinoma PMID 19218458 2009 A mitochondrial DNA mutation linked to colon cancer results in proton leaks in cytochrome c oxidase.

PMID 16407113 2006 Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.