Variant: rs34778348 

    present in Gene: LRRK2;LOC105369736
    present in Chromosome: 12
    Position on Chromosome: 40363526
    Alleles of this Variant: G/A

rs34778348 in LRRK2;LOC105369736 gene and PARKINSON DISEASE 8 (disorder) PMID 15541309 2004 Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.

PMID 15732108 2005 Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.

PMID 16533964 2006 LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance.

PMID 16240353 2005 G2019S LRRK2 mutation in French and North African families with Parkinson's disease.

PMID 16298482 2006 LRRK2 G2019S is a common mutation in Spanish patients with late-onset Parkinson's disease.

PMID 16157908 2005 LRRK2 mutations in Parkinson disease.

PMID 22956510 2012 Systematic review and UK-based study of PARK2 (parkin), PINK1, PARK7 (DJ-1) and LRRK2 in early-onset Parkinson's disease.

PMID 15726496 2005 Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations.

PMID 16272257 2005 The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor.

PMID 16251215 2005 Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*.

PMID 16333314 2006 Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

PMID 15680455 2005 Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease.

PMID 23279440 2013 EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease.

PMID 28202711 2017 Structural interface between LRRK2 and 14-3-3 protein.

PMID 26824392 2016 Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

PMID 15929036 2005 Genetic and clinical identification of Parkinson's disease patients with LRRK2 G2019S mutation.

PMID 16250030 2006 Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics.

PMID 15680457 2005 A common LRRK2 mutation in idiopathic Parkinson's disease.

PMID 28720718 2017 Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.

PMID 15852371 2005 Clinical features of LRRK2-associated Parkinson's disease in central Norway.

PMID 29212815 2018 Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.

rs34778348 in LRRK2;LOC105369736 gene and Parkinson Disease PMID 22438815 2012 Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.