Variant: rs397516981

present in Gene: MIR4728;ERBB2 present in Chromosome: 17 Position on Chromosome: 39724748 Alleles of this Variant: -/GGGCTCCCC

rs397516981 in MIR4728;ERBB2 gene and Non-Small Cell Lung Carcinoma PMID 18334834 2008 siRNA targeting against EGFR, a promising candidate for a novel therapeutic application to lung adenocarcinoma.

PMID 16638863 2006 Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation.

PMID 22325357 2012 Clinical activity of afatinib (BIBW 2992) in patients with lung adenocarcinoma with mutations in the kinase domain of HER2/neu.

PMID 22761469 2012 Prevalence, clinicopathologic associations, and molecular spectrum of ERBB2 (HER2) tyrosine kinase mutations in lung adenocarcinomas.

PMID 15753357 2005 Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.