Variant: rs4342822

present in Gene: LOC105372912;PROX1-AS1 present in Chromosome: 1 Position on Chromosome: 213850882 Alleles of this Variant: G/T

rs4342822 in LOC105372912;PROX1-AS1 gene and Breast Carcinoma PMID 29059430 2017 Among survivors who received 10 or higher gray breast radiation exposure, a locus on 1q41 was associated with subsequent breast cancer risk (rs4342822, nearest gene PROX1 , risk allele frequency in control subjects [RAF controls ] = 0.46, hazard ratio = 1.92, 95% confidence interval = 1.49 to 2.44, P = 7.09 × 10 -9 ).

rs4342822 in LOC105372912;PROX1-AS1 gene and Malignant Childhood Neoplasm PMID 29059430 2017 Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer.