present in Gene: SLC22A1
present in Chromosome: 6
Position on Chromosome: 160160511
Alleles of this Variant: -/G
rs4646284 in
SLC22A1 gene and
Prostate carcinoma
PMID 26034056 2015 A genome-wide association study (GWAS) of prostate cancer in Kaiser Permanente health plan members (7,783 cases, 38,595 controls; 80.3% non-Hispanic white, 4.9% African-American, 7.0% East Asian, and 7.8% Latino) revealed a new independent risk indel rs4646284 at the previously identified locus 6q25.3 that replicated in PEGASUS (N = 7,539) and the Multiethnic Cohort (N = 4,679) with an overall P = 1.0 × 10(-19) (OR, 1.18).