Variant: rs4704397 

    present in Gene: PDE8B
    present in Chromosome: 5
    Position on Chromosome: 77222617
    Alleles of this Variant: G/A

rs4704397 in PDE8B gene and Blood thyroid stimulating hormone analysis PMID 18514160 2008 Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.

rs4704397 in PDE8B gene and Thyroid stimulating hormone measurement PMID 18514160 2008 By genotyping 362,129 SNPs in 4,300 Sardinians, we identified a strong association (p = 1.3 x 10(-11)) between alleles of rs4704397 and circulating TSH levels; each additional copy of the minor A allele was associated with an increase of 0.13 muIU/ml in TSH.

rs4704397 in PDE8B gene and thyroid function PMID 22494929 2012 Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function.

PMID 18514160 2008 Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.