present in Gene: F7
present in Chromosome: 13
Position on Chromosome: 113105720
Alleles of this Variant: T/C;G
rs561241 in
F7 gene and
Factor VII measurement
PMID 17903294 2007 In association analysis, the lowest GEE p-value for hemostatic factors was p = 4.5*10(-16) for factor VII at SNP rs561241, a variant located near the F7 gene and in complete linkage disequilibrium (LD) (r2 = 1) with the Arg353Gln F7 SNP previously shown to account for 9% of total phenotypic variance.
PMID 30642921 2019 A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
rs561241 in
F7 gene and
Prothrombin time assay
PMID 22703881 2012 For PT, significant associations were identified and confirmed in F7 (rs561241, p = 3.71 × 10(-56)) and PROCR/EDEM2 (rs2295888, p = 5.25 × 10(-13)).
rs561241 in
F7 gene and
von Willebrand's factor (lab test)
PMID 23381943 2013 Ischemic stroke is associated with the ABO locus: the EuroCLOT study.