Variant: rs63750129 

    present in Gene: MAPT
    present in Chromosome: 17
    Position on Chromosome: 45996612
    Alleles of this Variant: A/C

rs63750129 in MAPT gene and Pick Disease of the Brain PMID 10604746 1999 Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits.

PMID 11117542 2000 Pick's disease is associated with mutations in the tau gene.

PMID 11089577 2000 Taken together, the present findings indicate that the K257T mutation in Tau can cause a dementing condition similar to Pick's disease.

PMID 11601501 2001 Pick's disease associated with the novel Tau gene mutation K369I.

PMID 11891833 2002 A novel tau mutation, S320F, causes a tauopathy with inclusions similar to those in Pick's disease.