Variant: rs63750342 

    present in Gene: FBXO11;MSH6
    present in Chromosome: 2
    Position on Chromosome: 47791092
    Alleles of this Variant: G/A

rs63750342 in FBXO11;MSH6 gene and Colorectal cancer, hereditary nonpolyposis, type 1 PMID 10348829 1999 New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.

PMID 14974087 2004 Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue.

PMID 15483016 2004 Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.