present in Gene: LPA
present in Chromosome: 6
Position on Chromosome: 160576086
Alleles of this Variant: A/G;T
rs74617384 in
LPA gene and
Coronary Artery Disease
PMID 30003307 2018 We found genome-wide significant evidence for association with CAD at the previously well-established LPA locus (lead variant: rs74617384; OR 1.38 [95% CI 1.26, 1.51], p = 3.2 × 10<sup>-12</sup>) and at 9p21 (lead variant: rs10811652; OR 1.19 [95% CI 1.13, 1.26], p = 6.0 × 10<sup>-11</sup>).
rs74617384 in
LPA gene and
Diabetes
PMID 30003307 2018 Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank.
rs74617384 in
LPA gene and
Diabetes Mellitus
PMID 30003307 2018 Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank.
rs74617384 in
LPA gene and
Low density lipoprotein cholesterol measurement
PMID 30670697 2019 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
rs74617384 in
LPA gene and
Serum total cholesterol measurement
PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.