Variant: rs76863441 

    present in Gene: PLA2G7
    present in Chromosome: 6
    Position on Chromosome: 46709361
    Alleles of this Variant: C/A

rs76863441 in PLA2G7 gene and Acute Coronary Syndrome PMID 28753643 2017 Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.

rs76863441 in PLA2G7 gene and Coronary heart disease PMID 28753643 2017 Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.

rs76863441 in PLA2G7 gene and Platelet-Activating Factor Acetylhydrolase Deficiency PMID 9759612 1998 A mutation in plasma platelet-activating factor acetylhydrolase (Val279Phe) is a genetic risk factor for cerebral hemorrhage but not for hypertension.

PMID 9472966 1998 Identification of the G994--> T missense in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men.

PMID 9245731 1997 Loss of activity of plasma platelet-activating factor acetylhydrolase due to a novel Gln281-->Arg mutation.

PMID 9412624 1997 A mutation in plasma platelet-activating factor acetylhydrolase (Val279-->Phe) is a genetic risk factor for stroke.

PMID 8675689 1996 Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase.