Variant: rs7937

present in Gene: RAB4B;MIA-RAB4B;RAB4B-EGLN2 present in Chromosome: 19 Position on Chromosome: 40796801 Alleles of this Variant: C/A;T

rs7937 in RAB4B;MIA-RAB4B;RAB4B-EGLN2 gene and Chronic Obstructive Airway Disease PMID 22080838 2012 Genotyping this single nucleotide polymorphism (SNP) and another nearby SNP in linkage disequilibrium (rs2604894) in 2859 subjects from the family-based International COPD Genetics Network study (ICGN) demonstrated supportive evidence for association for COPD (P = 0.28 and 0.11 for rs7937 and rs2604894), pre-bronchodilator FEV(1) (P = 0.08 and 0.04) and severe (GOLD 3&4) COPD (P = 0.09 and 0.017).

PMID 28166215 2017 Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

rs7937 in RAB4B;MIA-RAB4B;RAB4B-EGLN2 gene and Forced expiratory volume function PMID 26634245 2015 A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

rs7937 in RAB4B;MIA-RAB4B;RAB4B-EGLN2 gene and Smoking Behaviors PMID 20418888 2010 Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.