present in Gene: BRCA2
present in Chromosome: 13
Position on Chromosome: 32340183
Alleles of this Variant: C/-
rs80359541 in
BRCA2 gene and
Dysmorphic features
PMID 9497246 1998 Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
PMID 21952622 2011 BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients.
PMID 21568838 2011 Fanconi anemia: at the crossroads of DNA repair.
PMID 17416853 2007 Meta-analysis of BRCA1 and BRCA2 penetrance.
PMID 16141007 2005 Cancer risks in BRCA2 families: estimates for sites other than breast and ovary.
PMID 16825431 2007 Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2.
PMID 18042939 2007 Breast cancer risk among male BRCA1 and BRCA2 mutation carriers.
PMID 15197194 2004 Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.
PMID 15796958 2005 BRCA1 and pancreatic cancer: pedigree findings and their causal relationships.
PMID 12677558 2003 Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies.
rs80359541 in
BRCA2 gene and
Hereditary Breast and Ovarian Cancer Syndrome
PMID 16912212 2006 Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 years.
PMID 22430266 2012 Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers.
PMID 26681312 2016 Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
PMID 18703817 2008 The relative contribution of point mutations and genomic rearrangements in BRCA1 and BRCA2 in high-risk breast cancer families.
PMID 15197194 2004 Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.
PMID 12677558 2003 Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies.
PMID 18042939 2007 Breast cancer risk among male BRCA1 and BRCA2 mutation carriers.
PMID 17416853 2007 Meta-analysis of BRCA1 and BRCA2 penetrance.
PMID 9497246 1998 Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
PMID 16141007 2005 Cancer risks in BRCA2 families: estimates for sites other than breast and ovary.
PMID 21952622 2011 BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients.
PMID 21568838 2011 Fanconi anemia: at the crossroads of DNA repair.
PMID 9497246 1998 Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
PMID 15796958 2005 BRCA1 and pancreatic cancer: pedigree findings and their causal relationships.
PMID 16141007 2005 Cancer risks in BRCA2 families: estimates for sites other than breast and ovary.
PMID 12677558 2003 Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies.
PMID 21952622 2011 BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients.
PMID 16825431 2007 Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2.
PMID 18042939 2007 Breast cancer risk among male BRCA1 and BRCA2 mutation carriers.
PMID 17416853 2007 Meta-analysis of BRCA1 and BRCA2 penetrance.
PMID 15197194 2004 Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.