present in Gene: IRF4
present in Chromosome: 6
Position on Chromosome: 411064
Alleles of this Variant: A/G;T
rs872071 in
IRF4 gene and
Chronic Lymphocytic Leukemia
PMID 18758461 2008 We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).
PMID 22700719 2012 Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.
PMID 23770605 2013 Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
PMID 24292274 2014 A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
rs872071 in
IRF4 gene and
Erectile dysfunction
PMID 22704111 2012 Pilot genome-wide association search identifies potential loci for risk of erectile dysfunction in type 1 diabetes using the DCCT/EDIC study cohort.
rs872071 in
IRF4 gene and
Nasopharyngeal carcinoma
PMID 20512145 2010 A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
rs872071 in
IRF4 gene and
Small Lymphocytic Lymphoma
PMID 24292274 2014 A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
PMID 23770605 2013 Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
PMID 18758461 2008 A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.
PMID 22700719 2012 Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.