present in Gene: HLA-DPB1
present in Chromosome: 6
Position on Chromosome: 33087084
Alleles of this Variant: A/G
rs9277535 in
HLA-DPB1 gene and
Hepatitis B
PMID 19349983 2009 A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
PMID 21750111 2011 A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
PMID 23760081 2013 A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
PMID 22737229 2012 Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.
PMID 24940741 2014 We found that rs9277535 (HLA-DPB1, P = 4.87×10(-14)), rs9276370 (HLA-DQA2, P = 1.9×10(-12)), rs7756516 and rs7453920 (HLA-DQB2, P = 1.48×10(-11) and P = 6.66×10(-15) respectively) were significantly associated with persistent HBV infection.
rs9277535 in
HLA-DPB1 gene and
Hepatitis B, Chronic
PMID 25802187 2015 Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B.
PMID 24940741 2014 A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese.
rs9277535 in
HLA-DPB1 gene and
Liver carcinoma
PMID 23242368 2013 Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma.
rs9277535 in
HLA-DPB1 gene and
Rheumatoid Arthritis
PMID 19503088 2009 REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
PMID 17804836 2007 TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
rs9277535 in
HLA-DPB1 gene and
cervical cancer
PMID 23817570 2013 A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12.