Condition: Antley-Bixler Syndrome with Disordered Steroidogenesis
rs28931608 in
POR gene and
Antley-Bixler Syndrome with Disordered Steroidogenesis
PMID 14758361 2004 Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome.
PMID 20124576 2010 Ambiguous genitalia, impaired steroidogenesis, and Antley-Bixler syndrome in a patient with P450 oxidoreductase deficiency.
PMID 15483095 2005 Cytochrome P450 oxidoreductase gene mutations and Antley-Bixler syndrome with abnormal genitalia and/or impaired steroidogenesis: molecular and clinical studies in 10 patients.
PMID 20940534 2010 Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro.
PMID 28841001 2017 A Case of Antley-Bixler Syndrome With a Novel Likely Pathogenic Variant (c.529G>C) in the POR Gene.
PMID 15220035 2004 Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study.
PMID 22162478 2012 Genotype-phenotype analysis in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency.
PMID 19837910 2009 Clinical, genetic, and enzymatic characterization of P450 oxidoreductase deficiency in four patients.
PMID 21741353 2011 Mutations of human cytochrome P450 reductase differentially modulate heme oxygenase-1 activity and oligomerization.
PMID 20732302 2010 Altered heme catabolism by heme oxygenase-1 caused by mutations in human NADPH cytochrome P450 reductase.