Condition: Bisphosphonate-Associated Osteonecrosis of the Jaw


rs11064477 in PHB2 gene and Bisphosphonate-Associated Osteonecrosis of the Jaw PMID 22267851 2012 Genomewide pharmacogenetics of bisphosphonate-induced osteonecrosis of the jaw: the role of RBMS3.

rs17024608 in RBMS3 gene and Bisphosphonate-Associated Osteonecrosis of the Jaw PMID 22267851 2012 Association testing identified a significant marker in the RBMS3 gene, rs17024608 (p-value < 7 × 10(-8)); individuals positive for the SNP were 5.8× more likely to develop BRONJ (odds ratio, 5.8; 95% confidence interval, 3.1-11.1).