Condition: Brugada Syndrome 2


rs72552291 in GPD1L gene and Brugada Syndrome 2 PMID 17967976 2007 Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome.

PMID 17967977 2007 Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias.

PMID 19666841 2009 GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A.

PMID 19745168 2009 Cardiac Na+ current regulation by pyridine nucleotides.