Condition: Brugada Syndrome 2
rs72552291 in
GPD1L gene and
Brugada Syndrome 2
PMID 17967976 2007 Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome.
PMID 17967977 2007 Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias.
PMID 19666841 2009 GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A.
PMID 19745168 2009 Cardiac Na+ current regulation by pyridine nucleotides.