Condition: Carcinoma
rs121913480 in
FGFR3 gene and
Carcinoma
PMID 15880580 2005 Constitutive activating mutation of the FGFR3b in oral squamous cell carcinomas.
PMID 10471491 1999 Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.
PMID 12009017 2002 Differential activation of cysteine-substitution mutants of fibroblast growth factor receptor 3 is determined by cysteine localization.
PMID 11429702 2001 Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations.
PMID 19165726 2009 The strong dimerization of the transmembrane domain of the fibroblast growth factor receptor (FGFR) is modulated by C-terminal juxtamembrane residues.
PMID 9857065 1998 Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation.
rs1057519824 in
MET gene and
Carcinoma
PMID 12460923 2002 Novel somatic mutations of the MET oncogene in human carcinoma metastases activating cell motility and invasion.
PMID 9826708 1998 Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth.
PMID 1104268 1975 The radiology of osseous and articular infection.
PMID 10417759 1999 Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family.