Condition: MEIER-GORLIN SYNDROME 1
rs143141689 in
ORC1 gene and
MEIER-GORLIN SYNDROME 1
PMID 25689043 2015 A Meier-Gorlin syndrome mutation impairs the ORC1-nucleosome association.
PMID 21358631 2011 Mutations in origin recognition complex gene ORC4 cause Meier-Gorlin syndrome.
PMID 21358632 2011 Mutations in the pre-replication complex cause Meier-Gorlin syndrome.
PMID 21358633 2011 Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome.
PMID 22855792 2012 Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication.
PMID 23023959 2012 Meier-Gorlin syndrome: growth and secondary sexual development of a microcephalic primordial dwarfism disorder.