Condition: MENTAL RETARDATION, AUTOSOMAL DOMINANT 44


rs768858988 in TRIO gene and MENTAL RETARDATION, AUTOSOMAL DOMINANT 44 PMID 27418539 2016 Mutations specific to the Rac-GEF domain of TRIO cause intellectual disability and microcephaly.

PMID 26721934 2016 TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function.