Condition: MENTAL RETARDATION, AUTOSOMAL DOMINANT 44
rs768858988
in
TRIO
gene and
MENTAL RETARDATION, AUTOSOMAL DOMINANT 44
PMID 27418539
2016 Mutations specific to the Rac-GEF domain of
TRIO
cause intellectual disability and microcephaly.
PMID 26721934
2016 TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function.