Condition: Mesial temporal lobe epilepsy with hippocampal sclerosis
rs11692675
in
SCN1A-AS1;SCN1A
gene and
Mesial temporal lobe epilepsy with hippocampal sclerosis
PMID 24014518
2013 Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A.
rs7587026
in
SCN1A;SCN1A-AS1
gene and
Mesial temporal lobe epilepsy with hippocampal sclerosis
PMID 24014518
2013 Meta-analysis revealed a genome-wide significant association for
mesial temporal lobe epilepsy with hippocampal sclerosis
with febrile seizures at the sodium channel gene cluster on chromosome 2q24.3 [
rs7587026
, within an intron of the SCN1A gene, P = 3.36 × 10(-9), odds ratio (A) = 1.42, 95% confidence interval: 1.26-1.59].