Condition: PEROXISOME BIOGENESIS DISORDER 6B
rs1325771720 in
PEX10 gene and
PEROXISOME BIOGENESIS DISORDER 6B
PMID 7565793 1995 Formation of the peroxisome lumen is abolished by loss of Pichia pastoris Pas7p, a zinc-binding integral membrane protein of the peroxisome.
PMID 10862081 2000 Phenotype-genotype relationships in PEX10-deficient peroxisome biogenesis disorder patients.
PMID 9683594 1998 Identification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disorders.
PMID 21031596 2011 Genetic classification and mutational spectrum of more than 600 patients with a Zellweger syndrome spectrum disorder.
PMID 25525159 2015 RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease.
PMID 20695019 2010 Mutations in PEX10 are a cause of autosomal recessive ataxia.
PMID 17702006 2007 Zellweger syndrome resulting from maternal isodisomy of chromosome 1.
PMID 15542397 2004 The PEX Gene Screen: molecular diagnosis of peroxisome biogenesis disorders in the Zellweger syndrome spectrum.
PMID 17041890 2006 Identification of novel mutations in PEX2, PEX6, PEX10, PEX12, and PEX13 in Zellweger spectrum patients.
PMID 12794690 2003 Genetic heterogeneity of peroxisome biogenesis disorders among Japanese patients: evidence for a founder haplotype for the most common PEX10 gene mutation.
rs62636524 in
PEX10;PLCH2 gene and
PEROXISOME BIOGENESIS DISORDER 6B
PMID 15542397 2004 The PEX Gene Screen: molecular diagnosis of peroxisome biogenesis disorders in the Zellweger syndrome spectrum.
PMID 21465523 2011 Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutations.
PMID 25179809 2014 High prevalence of primary adrenal insufficiency in Zellweger spectrum disorders.
rs724160002 in
PLCH2;PEX10 gene and
PEROXISOME BIOGENESIS DISORDER 6B
PMID 20695019 2010 Mutations in PEX10 are a cause of autosomal recessive ataxia.
PMID 21031596 2011 Genetic classification and mutational spectrum of more than 600 patients with a Zellweger syndrome spectrum disorder.